Depression, Anxiety and Autism: Is the Answer in Your Poop?

The gut-brain connection is being researched more vigorously than ever. Dr. Valerie Taylor, an expert in psychiatry research and fecal transplant gives her opinion in this area.

Hippocrates has been famously quoted, especially by the functional medicine and holistic doctors, that, “All illnesses begin in the gut.” Today’s podcast guest, Dr. Valerie Taylor may be the perfect person to answer the specific question, how much of our mental health is affected by our microbiome? Dr. Taylor is a professor and department head of psychiatry at the Hotchkiss Brain Institute in Alberta, Canada. She is internationally known as an expert in this area of the brain-gut connection. I think she’s unusual in this aspect that not too many people who are psychiatrists are interested in poop. That’s what kind of makes her special.

I did have a prior podcast on the Power of Poop with Dr. Ari Greenspan several months ago, who’s a gastroenterologist at Mount Sinai. And it was a very interesting discussion but, obviously, a lot of it was focused on infections in the gut, and issues with that directly with the gut. But here we’re going to be talking about how what’s going on in your microbiome and assessing your stool, maybe telling us a lot more about your mood, and whether you have a mental illness.

And just a few facts before I bring Dr. Taylor in, the human gut has 100 trillion bacteria. So, sometimes you have to think, “What are they all doing there?” The other thing is there are 3 million genes that help build molecules to help us digest food, make vitamins such as vitamin K, and to keep bad bacteria out of our system. And, finally, this is, I think, super important, the bacteria in the gut make 90% of our serotonin in our body. And almost everyone knows serotonin is that neurotransmitter that, again, there are so many medications that are given to try to help boost your serotonin to keep us calm, and in a better mood.

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Asem Bala

MSc

Asem Bala, MSc has over 20 years of experience in Healthcare & Clinical Research Management, now working at Taylored Biotherapeutics to create partnerships and ensure regulatory approvals.

Dr. Valerie Taylor

MD, PhD, FRCP

Dr. Valerie Taylor, MD, PhD, FRCP is a Professor of Psychiatry at the University of Calgary. She completed a Bachelor of Medical Science and graduated from medical school at Memorial University of Newfoundland. She subsequently finished her residency training in Psychiatry and got her PhD in Neuroscience from McMaster University in Hamilton, Ontario. Prior to coming to Calgary, she was the chief of Psychiatry at the Women’s College Hospital and the chief of Adult Health Services at the Center for Addiction and Mental Health in Toronto.

Her academic focus has been on the area of medical psychiatry – specifically, for the last 5 years, on the gut brain axis and the the gut microbiome. She is the only funded researcher in North America examining the therapeutic effects of fecal transplant as a treatment for mental health and she currently has 4 novel clinical trials looking at modifying the gut microbiome to treat mood disorders as well as the largest biological neuroscience microbiome repository in North America. She has over 180 peer reviewed publications and funding from a variety of national and international funding agencies. In 2020 she started Taylored Biotherapeutics, a micro therapeutics drug company. Today her primary role is in leading product development, getting regulatory approval, and finding partnerships.